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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Huiyuan Jiang

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Open access Aug 2026

MFN2 inhibits colorectal cancer tumorigenesis by regulating glycolysis through TRIM21-mediated PFKP stability.

Overexpression of MFN2 suppressed CRC cell glycolysis and tumor growth by enhancing TRIM21-mediated degradation of PFKP andilitation of TRIM21 to PFKP to mediate its degradation, thereby hindering the malignant progression of CRC.

Huiyuan Jiang, Hongwei Guo, Yan Wang et al. · 0 citations

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