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Humberto Martínez-Orozco

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Review Open access Oct 2026

“Morphological, Functional, and Molecular Progression of Blood-Brain Barrier Dysfunction in Alzheimer’s Disease”

Blood-brain barrier (BBB) dysfunction is increasingly recognized as an early pathological event in sporadic Alzheimer’s disease (AD), which represents over 95% of cases. Vascular risk factors and cerebral insulin resistance are considered potential contributors to its initiation. This review synthesizes evidence availa...

Karen León-Arcia, Humberto Martínez-Orozco, Magdalena Guerra-Crespo et al. · 0 citations

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