Attenuation of systemic inflammation-induced behavioral deficits and neuromolecular alterations by N-acetylcysteine in a rodent model
Aims: Systemic inflammation driven by lipopolysaccharide (LPS) induces neurobehavioral deficits, hypothalamic-pituitary-adrenal (HPA) axis dysregulation, and neurodegeneration-related alterations. N-acetylcysteine (NAC) is a potent antioxidant with emerging anti-inflammatory properties. This study investigated whether...