Huu-Minh Nguyen-Tran

Tailoring biodegradable polycaprolactone-polyethylene glycol coating on mesoporous silica nanoparticles: optimization of chain length for enhanced enzyme-triggered drug release in cancer therapy.

Poly(ε-caprolactone) (PCL) is a biodegradable polymer extensively explored for drug delivery applications, particularly in cancer therapy. However, tailoring its degradation kinetics is critical for designing efficient stimuli-responsive nanocarriers. In this study, we systematically optimized the chain length of PCL t...