Open access
Sep 2026
Pharmacological modulation of GPR84 revealed by dual states structures and immune functional assays
Cryo-electron microscopy structures of GPR84 in both active and inactive states revealed how different ligands interact with GPR84, influencing its signaling pathways, and provided a structural basis for designing selective modulators of GPR84, which could lead to new therapeutic strategies for diseases involving immun...
Myung Kyung Choi, D. Park, Pankyung Kim et al.
· Experimental and Molecular M... · 0 citations