Sep 2026
Varlitinib attenuates neuroinflammation and dopaminergic neurodegeneration in experimental Parkinsonism.
Neuroinflammation mediated by microglial activation plays a critical role in Parkinson's disease (PD), with the NLRP3 inflammasome contributing to dopaminergic neurodegeneration. Varlitinib, a clinically developed pan-human epidermal growth factor receptor inhibitor, has been investigated as an anticancer agent; howeve...
Hye-Sun Lim, Jinyoung Park, Wonhwa Lee et al.
· Neuroscience Letters · 0 citations