Redefining post-xenotransplantation surveillance: leveraging metagenomic next-generation sequencing to discriminate true pathogen replication from microchimerism-induced false positives.
Infection-related risks remain a major concern in xenotransplantation and require continued vigilance as the field progresses toward clinical application. Xenozoonosis is of particular concern, especially in relation to donor-derived porcine viruses such as porcine endogenous retroviruses, porcine cytomegalovirus, porc...