Hyeung-geun Park

Enantioselective Organocatalytic Construction of N-Bridged Tricyclic Normorphan Skeleton: Application to the Total Synthesis of (+)-Peduncularine.

The normorphan framework is a compact, sp3-rich N-bridged scaffold found in biologically active natural products and increasingly valued as a three-dimensional platform for medicinal chemistry. Despite its synthetic and biological relevance, direct catalytic asymmetric access to functionalized normorphan-related archit...