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Hyunkee Kim

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Open access Jul 2026

Lecanemab in symptomatic PSEN1 p.Met233Val early‐onset Alzheimer's disease: Neuroimaging safety, regional amyloid‐PET dynamics, and longitudinal plasma biomarkers

Abstract Introduction The presenilin 1 (PSEN1) p.Met233Val variant is a Dominantly Inherited Alzheimer Network–Trials Unit (DIAN‐TU)–eligible autosomal‐dominant Alzheimer's disease (ADAD) variant for which lecanemab response data are unavailable. Methods A 34‐year‐old symptomatic PSEN1 p.Met233Val carrier (APOE ε3/ε3)...

Min-Young Noh, Wonjae Sung, Hyunkee Kim et al. · 0 citations

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