Sep 2026
Adaptive laboratory evolution enables autotrophic growth of Eubacterium limosum under defined medium conditions.
Recordomic analysis revealed a significant upregulation of the tryptophan biosynthesis pathway in ECO_X within the yeast extract-free defined medium, indicating that limited tryptophan availability is a key constraint underlying the yeast extract dependence of the parental strain under autotrophic conditions.
Seulgi Kang, Jiyun Bae, Donghwi Lee et al.
· Bioresource Technology · 0 citations