Open access
Aug 2026
AI-Driven Multi-Omics Integration of Synthetic Colon Adenocarcinoma for Cluster-Guided PROTAC Candidate Design Targeting KRASG12D
A reproducible artificial intelligence framework that integrates multi-omics benchmarking, sample-level drug prioritization, E3 ubiquitin ligase selection, and shape-anchored Proteolysis Targeting Chimera (PROTAC) design for KRASG12D in colon adenocarcinoma is presented.
Khaled M. Elamin, S. Elbashir, I. Adam
· International Journal of Mol... · 0 citations