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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

I. Aifantis

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2 papers indexed here

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Aug 2026

Splenic extramedullary hematopoiesis in myelofibrosis is shaped by transcriptomic and epigenetic dysregulation.

Myelofibrosis (MF) is a chronic, progressive myeloproliferative neoplasm characterized by bone marrow fibrosis, ineffective blood cell production, and neoplastic extramedullary hematopoiesis (EMH) occurring primarily within the spleen. To explore the molecular mechanisms underlying splenic EMH, we performed single-cell...

Rebecca Austin, Madeline H. Kowalski, Xiaoli Wang et al. · 2 citations
Open access Sep 2026

Type 2 immune history trains lung macrophages for viral disease tolerance.

Severe respiratory viral disease varies widely among individuals and often reflects immunopathology rather than inadequate pathogen control, suggesting that previous immune history can prime the lungs towards disease tolerance. Here we show that nerve- and airway-associated macrophages (NAMs), a subset of interstitial...

P. Damani-Yokota, Y. Yordanov, Eduardo D. Bernier et al. · 0 citations

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