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Author

I. Akkouh

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Open access Aug 2026

Genetic liability to addiction underlies comorbid bipolar and substance use disorders.

By dissecting the genetic liability to SUD and SU and investigating their relationship with BIP, this work finds a genetic signature correlated with substance dependence but not substance use more broadly.

L. Ystaas, P. Parekh, N. Parker et al. · 0 citations
Open access Jul 2026

Integrative multiomics profiling of cortical brain organoids reveals a druggable alternative splicing program in schizophrenia

This work derived cortical brain organoids from a large cohort of schizophrenia (SCZ) patients and healthy controls and employed a comprehensive multiomics strategy to dissect the cellular mechanisms of long-term CLZ exposure, uncovered a SCZ-specific and metabolism-independent alternative splicing program that was ame...

I. Akkouh, Jordi Requena Osete, A. Szabo et al. · 0 citations

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