Open access
Jul 2026
Transciptomic Profiling of CRISPR-Cas9 Mediated LEF1 Knockout in Chronic Lymphocytic Leukemia: Revealing Compensatory Survical Pathways
The study suggests that the inhibition of the Wnt/LEF1 axis is associated with the potential activation of a compensatory survival mechanism, involving the NF-kappa B/AP-1 pathway.
I. Alhamadani, Mohammad Alzeyadi
· Asian Pacific Journal of Can... · 0 citations