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Author

I. Cortés-Ciriano

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Open access Aug 2026

A compendium of next-generation patient-derived models for diverse cancers

A large-scale international programme—the Human Cancer Models Initiative—is presented, which involved the generation of a resource of 665 next-generation models from 2,780 donors with 25 cancer types and integrated tumour–model whole genome, exome, methylome and transcriptome analyses.

Dina Elharouni, Mushriq Al-Jazrawe, Seongmin Choi et al. · 7 citations
Review Aug 2026

Artificial intelligence in drug discovery - what it is, where we stand and the path forward.

Recommendations are provided for the development of AI in drug discovery with the aim of increasing its translational relevance, including benchmarking studies of AI tools in drug discovery need to move on from model validation and instead focus on their ability to improve decision making.

Andreas Bender, Morgan C. Thomas, J. Scannell et al. · 10 citations

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