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Author

I. Di Meo

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Review Open access Aug 2026

From Common Pathway to Divergent Diseases: Metabolic Aspects of Inborn Errors of CoA Biosynthesis

Therapeutic strategies are likely to require disease‐specific approaches, including precursor bypass or PANK activation where pathway flux can be restored, early pantethine supplementation in cardiomyopathic forms, and downstream or gene‐directed strategies for COASY‐related disorders.

I. Di Meo, Y. Anikster, Valeria Tiranti et al. · 0 citations
Open access May 2026

Exploring Heteroplasmic Variants in mtDNA: Insights from Single-Cell Transcriptomics

The power of single-cell technologies to better understand the complex link between mtDNA genetic diversity and mitochondrial phenotypic variability, and to study crucial aspects in mitochondrial biology and pathology, such as clonal dynamics, at single-cell resolution are highlighted.

M. Barresi, I. Di Meo, A. Nasca et al. · 0 citations

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