Design, synthesis, and structural characterization of novel 4-aminoantipyrine derivatives: Experimental and computational insights via DFT and molecular docking
4-Aminoantipyrine (4-AAP) derivatives are of significant interest in medicinal chemistry because of their diverse therapeutic potentials. In this study, we report the synthesis of five novel 4-aminoantipyrine derivatives ( P1–P5 ). The synthetic approach involved the initial preparation of enaminone ( I1 ) via a...