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Open access Oct 2026

Design, synthesis, and structural characterization of novel 4-aminoantipyrine derivatives: Experimental and computational insights via DFT and molecular docking

4-Aminoantipyrine (4-AAP) derivatives are of significant interest in medicinal chemistry because of their diverse therapeutic potentials. In this study, we report the synthesis of five novel 4-aminoantipyrine derivatives ( P1–P5 ). The synthetic approach involved the initial preparation of enaminone ( I1 ) via a...

I. Filali · 0 citations

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