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Author

I. Lanza

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Open access Sep 2026

Blocking PD-L2 prevents senescent cell accumulation and age-related dysfunction.

It is found that PD-L2 is upregulated in isolated senescent human cells and during aging, and senolytics can remove age-associated, highly PD-L2-expressing senescent cells.

Selim Chaib, Larissa P. G. Langhi Prata, Masayoshi Suda et al. · 0 citations
Open access Aug 2026

Multilevel impairment of mitochondrial respiration in inclusion body myositis.

Oxidative phosphorylation (OXPHOS) is a central function and a key indicator of mitochondrial fitness, yet studies in human tissue remain limited. Inclusion body myositis (IBM) is a progressive myopathy that lies at the intersection of aging, inflammation and mitochondrial dysfunction. We aimed to perform a comprehensi...

Ibrahim Shammas, Hazem Iaali, J. Watzlawik et al. · 0 citations

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