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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Ivano Legnini

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Open access Oct 2026

Genome architecture shapes transcriptional responses to topoisomerase depletion in C. elegans.

DNA supercoiling is an intrinsic consequence of transcription that must be resolved to maintain proper gene expression. How supercoiling shapes transcription dynamics in animal genomes remains unclear. Here, we acutely depleted topoisomerases in Caenorhabditis elegans and applied nascent transcription profiling, nuclea...

A. Morao, A. Chervova, Ana Kotte et al. · 0 citations
Open access Aug 2026

The human RNA-DNA interactome is cell type-specific and dynamic

The RNA-DNA interactome is established as a new genome regulatory layer that defines and maintains cellular identity and behavior and is shown to be highly dynamic yet reproducibly organized in cell-type specific networks.

A. Lambolez, P. Sahlén, Wenjing Kang et al. · 1 citation

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