Exploring molecular interactions between yeast topoisomerase I and RNA polymerase III subunit, Rpc82 using an in-silico approach
The process of DNA transcription leads to the generation of torsional stress, which must be resolved for smooth progression of the transcription machinery. In Saccharomyces cerevisiae, DNA topoisomerase I (Top I), a type IB topoisomerase, plays a critical role in relaxing supercoils and mitigating the topological s...