Beyond fibrinolysis: the multifaceted role of the fibrinolytic system in systemic sclerosis.
PURPOSE OF REVIEW This review summarizes the emerging role of the fibrinolytic system in the pathogenesis of systemic sclerosis (SSc) and its potential as a source of novel therapeutic targets. RECENT FINDINGS Increasing evidence indicates that SSc is characterized by impaired fibrinolysis, largely driven by upregula...