Author

I. Schalk

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Open access Aug 2026

PqqU (PA2289) is the primary PQQ transporter in Pseudomonas aeruginosa and links carbon metabolism to iron homeostasis.

Pseudomonas aeruginosa relies on the redox cofactor pyrroloquinoline quinone (PQQ) for efficient glucose and ethanol metabolism via periplasmic dehydrogenases (Gcd and ExaA). While PQQ biosynthesis is well-characterized, its uptake mechanisms remain unclear. Here, we identify PA2289 (PqqU), a TonB-dependent transporter...

C. Paschalidis, Manon Ferry, Anne-Eloïse Revillot-Schmidt et al. · FEMS Microbiology Letters · 0 citations

Open access Aug 2026

Identification of iron and zinc responsive TonB-dependent transporters in Pseudomonas aeruginosa.

Pseudomonas aeruginosa employs a repertoire of TonB-dependent transporters (TBDTs) to acquire essential nutrients, such as iron-siderophore complexes, enabling its adaptation to diverse and often hostile environments. While the roles of some TBDTs in virulence and metal acquisition are well-established, many remain poo...

Manon Ferry, Hortense Ferriz, Connor Sharp et al. · Biometals · 0 citations

Open access Aug 2026

Distinct transcriptional logics of catechol siderophore transporters in Pseudomonas aeruginosa for efficient iron acquisition.

Different transcriptional logics that allow P. aeruginosa to sense and decode a wide array of environmental catechols, integrate this information with iron availability, and thereby deploy an iron-uptake strategy finely tuned to competitive and host-associated niches are revealed.

Florian Volck, Anne-Eloïse Revillot-Schmidt, Thibaut Hubert et al. · Proceedings of the National... · 0 citations