Open access
Sep 2026
Cross‐Kingdom Structural Conservation and Diversification of Homeodomains Across Major Eukaryotic Lineages
Homeodomain transcription factors share an ancient helix‐turn‐helix DNA‐binding core yet regulate diverse developmental and reproductive programs across eukaryotes. We curated 355 nonredundant homeodomain structures spanning fungi, animals, and plants, including 118 experimental PDB entries and 237 high‐confidence Alph...
Gloria Elisabeth Buarante, E. Damayanti, P. A. Kurniatin et al.
· Evolution & Development · 0 citations