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Author

I. Sierra

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Review Open access Oct 2026

Recent Advances in the Enantiomeric Separation of Tropane Alkaloids by Liquid Chromatography: Analytical Strategies and Applications in Pharmaceutical, Biological, and Food Samples

This review examines recent advances in the enantiomeric separation of tropane alkaloids (TAs), focusing on atropine, a racemic mixture of (+)- and (−)-hyoscyamine whose enantiomers differ significantly in pharmacological activity, with (−)-hyoscyamine being the more potent antimuscarinic agent. Enantiomeric purity and...

Fernando L. Vera-Baquero, Lorena González-Gómez, I. Sierra et al. · 0 citations

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