Author

I. Svane

2 papers indexed here

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Open access Jun 2026

Optimized procurement of cancer-reactive T-cell receptors from clinical samples

Abstract T-cell receptors can sense cancer-associated changes in cellular proteins, lipids, metabolites, and stress pathways, enabling immune-mediated tumour elimination in some patients. These receptors underpin T-cell receptor-based immunotherapies, yet their isolation from clinical samples remains challenging due to...

Marine E. Caillaud, C. Rius, Théo Morin et al. · Immunotherapy Advances · 0 citations

Open access Sep 2026

Receptor-defined targeting of a genomically unique melanoma-enriched noncanonical antigen

Effective T cell–based immunotherapies require functional receptors that can be engineered and redeployed to recognize tumor-restricted antigens. Noncanonical peptides arising from transcription outside annotated protein-coding regions expand the antigenic landscape of cancer; however, systematic strategies to biologic...

T. Hulen, M. D. Crowther, Luke Alexander Schuster et al. · Signal Transduction and Targ... · 0 citations