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Meta-analysis Open access Aug 2026

The effect of mefloquine dose on outcome of uncomplicated falciparum malaria treated with artesunate-mefloquine: a WWARN systematic review and individual patient data meta-analysis

A combination of mefloquine associated with artesunate (AS-MQ) was the first artemisinin-based combination therapy (ACT) to be used widely for acute uncomplicated P. falciparum malaria. Individual patient data from 31 studies of patients with uncomplicated falciparum malaria treated with various AS-MQ regimens (target...

E. Ashley, Emmanuel Baron, M. Bouyou-Akotet et al. · 0 citations
Aug 2026

Safety and immunogenicity of one or two doses of the rVSVΔG-ZEBOV-GP Ebola virus vaccine in adults and adolescents living with HIV: a phase 2, multicentre, double-blind, randomised, placebo-controlled trial.

BACKGROUND A single dose of the replication-competent rVSVΔG-ZEBOV-GP vaccine is recommended by the WHO Strategic Advisory Group of Experts on Immunization during Ebola virus disease outbreaks. We aimed to assess the immunogenicity, safety, and tolerability of this vaccine in adults and adolescents with HIV. METHODS...

C. Tremblay, I. Valéa, B. Ndiaye et al. · 0 citations

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