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Author

I. Vilotijević

2 papers indexed here

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Open access Sep 2026

Accessing Sterically Congested Benzannulated Cyclic Aryl Ethers via Photoredox Decarboxylative Giese-Type C2–C3 Bond Formation

The visible-light-driven photocatalytic decarboxylation of α-aryloxy carboxylic acids produces α-oxy carbon-centered radicals that undergo intramolecular Giese addition to form 2,3-dihydrobenzofurans, chromans, 2,3,4,5-tetrahydrobenzo[b]oxepines, and 3,4,5,6-tetrahydro-2H-benzo[b]oxocines. In contrast to the existing m...

Igor Topalović, Markus Lange, I. Vilotijević · 0 citations
Open access Sep 2026

Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic.

Polymyxins are potent nonribosomal peptide antibiotics, yet their clinical use is limited by a narrow therapeutic window and nephro-/neurotoxicity. Conventional efforts to improve these agents rely on the incorporation of nonnatural building blocks that cannot be accessed biosynthetically and therefore must be introduc...

Maximilian Müll, Pia Lanvers, Giulia Ravagnan et al. · 0 citations

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