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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Iain C. Clark

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Open access Aug 2026

The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy

Significance The persistence of HIV in CD4+ T cells during antiretroviral therapy (ART) remains a barrier to cure. To study this reservoir, we developed an open-source DAb-seq platform that sequences proviral DNA and surface epitopes in single cells and profiled ~527,000 CD4 T cells from individuals on ART. HIV-infecte...

C. Delley, Sakshi Shah, Kevin M. Joslin et al. · 0 citations
Open access Aug 2026

Functional Pairing of TCR-peptide-MHC Interactomes by Single-cell Clonal Expansion

T cell antigen-specific immunity depends on pairwise interactions between T cell receptors and peptide- MHC, yet isolating the TCR-pMHC pairs that drive productive engagement remains a major obstacle for antigen-specific therapeutics and for decoding TCR specificity. We overcome this by co-encoding TCR and pMHC in a si...

L. Liu, Seung Won Shin, Kevin M. Joslin et al. · 0 citations

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