Author

Ian A. York

2 papers indexed here

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Open access Aug 2026

Memory B Cell Repertoire of a Repeatedly Vaccinated Individual Includes Influenza Hemagglutinin-Specific Cross-Group Binders with Affinity Beyond A(H1N1)pdm09 and A(H3N2) Seasonal Strains

Background/Objectives: Humans are primarily infected by two distinct seasonal influenza A virus (IAV) subtypes, A(H1N1)pdm09 and A(H3N2). Because IAV mutates rapidly, it continuously escapes existing protective antibodies. However, repeated exposure to these evolving strains increases the diversity of virus-specific me...

M. Mishina, C. Horn, Zachary Ende et al. · Vaccines · 0 citations

Open access Aug 2026

N-linked glycosylation sites with low occupancy support sustained circulation of the A(H3N2) influenza A virus in the human population

ABSTRACT Glycosylation of the influenza A virus hemagglutinin is crucial for viral fitness and immune evasion. The hemagglutinin of contemporary human A(H3N2) influenza A viruses is extensively glycosylated with up to 13 putative glycosylation sites. Glycan types and occupancy of these sites are not uniform: while most...

I. Alymova, Betlehem Mekonnen, Dong-Xia Wang et al. · Journal of Virology · 0 citations