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Author

Ichiro Hiratani

2 papers indexed here

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Open access Sep 2026

Repeat element–anchored enhancer–promoter interactions (REEPIs) shape the regulatory landscape of hormone-resistant breast cancer

These findings reveal a repeat-guided regulatory architecture associated with transcriptional adaptation in endocrine resistance and identify REEPIs as a previously underexplored component of regulatory reprogramming in hormone-resistant breast cancer.

Xu-Feng Shu, Sheng-Lian Ni, M. Murata et al. · 0 citations
Open access Sep 2026

Single-cell mapping of chromosome breaks identifies multiple fragile site classes with distinct DNA replication timing landscapes

Common fragile sites (CFSs) are genomic regions susceptible to chromosome breaks. However, because they were identified using cell populations, low-frequency fragile sites (non-CFSs) could have been overlooked. Here we perform single-cell genome-wide mapping and classification of aphidicolin-induced chromosome breaks....

Jothivanan Elumalai, Ichiro Hiratani · 0 citations

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