Idelberto Do Val Ribeiro-Junior

Methadone versus morphine for postoperative analgesia in gynecological laparoscopy: protocol for a randomized controlled trial

Background: Methadone has unique pharmacological properties among opioids, including N-methyl-D-aspartate receptor antagonism and a long half-life, which may enhance postoperative analgesia. Evidence regarding its efficacy and safety in gynecological laparoscopic surgery remains limited. This study protocol will compar...