Sep 2026
Abstract A019: Tumor Nutrient Stress Regulates Cancer-associated Fibroblast Heterogeneity
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer type with a 5-year survival rate of only 13%. PDAC is unique in that up to 90% of the tumor bulk is comprised of a dense desmoplastic stroma. Enriched within PDAC’s extensive stroma are cancer-associated fibroblasts (CAFs). CAFs orchestrate tumor progression...
Marta R. Storl-Desmond, Nicole Liu, K. Forti et al.
· Cancer Research · 0 citations