Open access
Oct 2026
Flexible 3D multimodal organoid interface reveals functional subnetworks and coordinated circuit activity in cortical organoids
The balance between excitatory and inhibitory (E/I) neurons is fundamental to cortical function, and its disruption underlies a wide range of neurological disorders, including epilepsy, Alzheimer’s disease and autism spectrum disorder. Cortical organoids offer a promising model to study this balance, as they recapitula...
M. Wilson, E. Kharitonova, Joseph Yeh et al.
· bioRxiv · 0 citations