Ilaha Sadigi

Mesenchymal stromal cell-derived extracellular vesicles attenuate inflammation-associated cognitive impairment and hippocampal microglial-synaptic remodeling

Microglia are central regulators of synaptic structure and cognitive function, yet under chronic inflammatory conditions, they can adopt stress-associated states associated with neuronal and synaptic vulnerability. Although inflammation-driven cognitive decline is often attributed to synapse loss, increasing evidence...