Author

Ilan Bruchim

2 papers indexed here

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Review Oct 2026

Rethinking Treatment Intensification in Poorly Chemosensitive Ovarian Cancer: A Review.

Importance Despite the integration of bevacizumab and poly(ADP-ribose) polymerase inhibitors into first-line treatment of advanced high-grade serous ovarian cancer, survival remains poor for the substantial subset of patients whose tumors respond insufficiently to platinum-based chemotherapy and who, therefore, frequen...

Benoît You, A. Clamp, K. Moore et al. · JAMA Oncology · 0 citations

Open access Sep 2026

BCAM-AKT2 fusion protein promotes unfolded protein response driven oncogenic signaling in SKOV3 epithelial ovarian cancer cell line

In view of the rapidly increasing evidence that gene fusion mutations are frequent drivers of cancer, a deeper understanding of the molecular and functional hallmarks of specific gene fusions in epithelial ovarian cancer (EOC) is essential. In this work we sought to identify the molecular signature of the BCAM-AKT2 fus...

Hala Khazem, Ravid Solomon Zemler, L. David et al. · PLoS ONE · 0 citations