Domain-Swapping of a GT-B Glycosyltransferase Broadens Its Sugar Donor Range for Glycodiversification of Natural Products.
Glycosylation of natural compounds modulates their bioactivity as well as their physicochemical properties, making glycodiversification a valuable strategy for identifying glycosidic derivatives with improved functional profiles. However, the use of glycosyltransferases (GTs) for their synthesis is constrained by strin...