Gene–Environment Interaction Mendelian Randomization Reveals Statin-Dependent Associations Between Metabolites and Lipid Traits
Introduction/Background: Observational links between circulating metabolites and lipid traits are often confounded by environmental factors. This study applied Mendelian randomization (MR) and gene–environment interaction MR (MR-G×E) to assess the average causal effects of genetically predicted metabolites on lipid tra...