Open access
Oct 2026
The anterior insular cortex mediates higher-order threat learning and memory
It is demonstrated that AIC excitatory neurons, specifically layer 5 pyramidal neurons projecting to the basolateral amygdala, are essential for higher-order threat learning/memory and a novel circuit mechanism for bidirectional regulation of higher-order threat learning/memory is identified.
Ho Namkung, Bandhan Mukherjee, Josephine de Chabot et al.
· bioRxiv · 0 citations