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Author

Iman M. Talaat

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Sep 2026

Pharmacological inhibition of CBP sensitizes breast cancer to DNA-damaging agents by compromising DNA repair and cell cycle pathways.

In vitro and in vivo breast cancer models show that CBP inhibition disrupts DNA repair and cell-cycle regulatory pathways, thereby enhancing doxorubicin-induced cytotoxicity and apoptosis, and support a rational epigenetic-chemotherapy combination approach.

Wafaa S. Ramadan, Iman M. Talaat, A. Al-Azawi et al. · 0 citations

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