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Author

Imran Uddin

1 paper indexed here

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Sep 2026

FasL-mediated death of activated intratumoral T cells drives secondary resistance to cancer immunotherapy.

Cancer progression following an initial response to immunotherapy (secondary resistance; 2°R) is a major and poorly understood problem. We treated mice bearing B16 melanoma with a combination of a regulatory T cell (Treg) depleting, non-IL-2 blocking antibody (anti-CD25NIB) and an autologous cancer cell vaccine (GVAX)....

Chen Qing, E. Ghorani, K. Foster et al. · 0 citations

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