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Ingo Marzi

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Open access Jul 2026

Development and biological validation of a dexamethasone-loaded, PLA-based 3D-printable composite filament for bone tissue engineering

The feasibility of integrating DEXA into a controlled drug release system for bone tissue engineering applications is demonstrated, and the FFF-compatible 1% DEXA–PLA CF retains physicochemical integrity after DEXA incorporation and enables sustained local DEXA delivery within a biologically active concentration range, achieving dual osteogenic and immunomodulatory effects.

S. Bianconi, Cem Asci, Fiona Ott et al. · 0 citations