Author

Ingunn M. Stromnes

4 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Sep 2026

Targeting pancreatic cancer with adenoviral vectors equipped with transgenes.

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, and current therapeutics provide limited benefits to patients. Desmoplasia and the highly immunosuppressive tumor microenvironment (TME) play a huge role in PDAC being elusive to current therapeutics. Here, we strategically selected four transge...

Brett L. Roach, Mizuho Sato-Dahlman, Kari L. Jacobsen et al. · Molecular Cancer Therapeutic... · 0 citations

Sep 2026

Abstract B084: Tracking tumor-specific CD4 T cells in pancreatic cancer reveals an essential role for cognate interactions with myeloid cells in remodeling the tumor microenvironment following immunotherapy

Our study identified an antigen (Ag)-specific CD4 T cell population in a preclinical orthotopic model of pancreatic ductal adenocarcinoma (PDA) that, upon expansion, elicited robust antitumor control. We developed an affinity-enhanced MHC-II tetramer to follow the endogenous tumor-specific CD4 T cells during pancreat...

Eduardo Cruz-Hinojoza, Zoe C. Schmichen, Sindri M. Bonner et al. · Cancer Research · 0 citations

Jul 2026

Defining the role of continued antigen engagement in regulating tumor-specific CD8+ T cell differentiation, migration, and survival 2256732

Understanding of the development of T cell exhaustion and the plasticity of lineage commitment in cancer to better inform future anti-cancer therapeutics is added.

Matthew B. Watowich, Jenny Krause, O. Smith et al. · Journal of Immunology · 0 citations

Open access Aug 2026

Tumor-specific CD4 T cells cooperate with myeloid cells to remodel the pancreatic tumor microenvironment and enable effective immunotherapy

T tumor-specific CD4 T cells are central mediators of effective immunotherapy in solid tumors, and human immunotherapy transcriptomics shows conserved Th1 programming and Treg destabilization as a feature of response.

Eduardo Cruz-Hinojoza, Zoe C. Schmiechen, Sindri M. Bonner et al. · bioRxiv · 0 citations