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Author

Inhee Choi

2 papers indexed here

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Open access Aug 2026

ABRL8301, a Novel 2-Methoxyestradiol Derivative, Mitigates Progressive Pulmonary Fibrosis by Downregulating 11β-Hydroxysteroid Dehydrogenase 1.

Progressive pulmonary fibrosis (PPF) is a severe lung disease characterized by persistent tissue damage and scarring, with no curative therapies currently available. The multifactorial and poorly understood pathogenesis complicates drug development, highlighting the need for novel multi-targeted anti-fibrotic therapeut...

So-Won Heo, Junghwan Choi, Yeonhwa Song et al. · 0 citations
Open access Sep 2026

HIF-1α-ASS1 axis drives reprogramming of arginine metabolism controls hepatic stellate cell activation in hepatic fibrosis.

ABRL8301 acts as a pharmacologic inducer of ASS1 and arginine biosynthesis, inhibiting EMT and fibrotic progression while enhancing anticancer therapy and support ABRL8301 as a promising antifibrotic and tumor-sensitizing agent in hepatic fibrosis.

Seungeun Lee, Yeonhwa Song, Sanghwa Kim et al. · 0 citations

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