Open access
Aug 2026
Loss of ABCA4 from photoreceptor discs is associated with glial transcriptomic changes in retinal organoids
It is suggested that ABCA4 deficiency in photoreceptor discs may trigger early stress-associated transcriptomic responses in retinal glial cells prior to overt photoreceptor degeneration, potentially contributing to Stargardt disease pathogenesis.
Rossella Valenzano, A. McDonald, C. Gallego et al.
· Stem Cells · 0 citations