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Author

Ioannis Ntekas

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Open access Sep 2026

Reducing Nuclear Rupture Rescues Gene Expression and Survival in LMNA-DCM.

A model in which nuclear envelope rupture in cKO cardiomyocytes triggers cytosolic DNA sensing pathways and maladaptive cell-cell communication with fibroblasts and immune cells, driving inflammation, fibrosis, and cardiac dysfunction is supported.

Noam Zuela-Sopilniak, J. Morival, Ioannis Ntekas et al. · 0 citations

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