Open access
Sep 2026
RMI2 regulates recombination intermediate metabolism to ensure proper chromosome segregation in mammalian meiosis
Abstract Proper segregation of meiotic chromosomes depends on the controlled formation and resolution of recombination intermediates that give rise to crossovers (COs). While the BTRR complex—comprising the BLM helicase, topoisomerase IIIα, and the proteins RMI1 and RMI2—is a well-characterized regulator of recombinati...
L. P. de Almeida, Tolkappiyan Premkumar, Monika K. Kawecka et al.
· Nucleic Acids Research · 0 citations