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Author

Ismail A. Abdelhamid

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Aug 2026

Synthesis, Cytotoxicity, and Docking Studies of Novel Chalcones Incorporating 2‐(1 H ‐Indol‐1‐yl)‐ N ‐arylacetamide and Benzo[ d ]thiazole Moieties

Lead compound 7a significantly induced apoptosis and cell‐cycle arrest in MCF‐7 cells, as evidenced by increased apoptotic fraction, elevated sub‐G1 content, and accumulation of cells in the G2/M and S phases, and represents a promising multitarget anticancer lead for further optimization.

Noha Yehia Badr, A. Almehdi, Mohamed A. Ragheb et al. · 0 citations

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