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İsmail Yapıcı

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Open access Sep 2026

Chemical profiling, biological evaluation, and QSAR-informed metabolite prioritization of Hypericum ekerii: a first report on antioxidant, enzyme inhibitory, and cytotoxic activities

Hypericum ekerii Yüce and Aytaç, first described in 2017, remains poorly characterized in terms of its phytochemical composition and biological properties. This study investigated aerial-part extracts of H. ekerii prepared with ethyl acetate, acetone, 70% acetone–water, and water. The hydroacetone extract showed the hi...

G. Zengin, Sakina Yagi, Mehmet Veysi Cetiz et al. · 0 citations
Open access Sep 2026

Beyond the fruit: phenolic composition, cytotoxicity, antioxidant, and multi-enzyme inhibitory activity of twig and leaf extracts from four understudied Turkish Rosa species

The phytochemical profile and multi-target bioactivity of four Turkish Rosa species, R. canina, R. hemisphaerica, R. horrida, and R. pulverulenta, were evaluated across vegetative organs (twigs and leaves) and three solvent polarities (ethyl acetate (EA), methanol (MeOH), water), in total 24 extracts. Untargeted Ultra-...

Hajar Salehi, M. Terzić, Gunes Ak et al. · 0 citations
Open access Sep 2026

Salvia limbata extracts and essential oil as a novel source of bioactive agents: metabolomic fingerprint, in vitro, in silico and network pharmacological perspectives

The genus Salvia has received considerable attention and has been studied extensively owing to its rich polyphenolic content. In the present study, Salvia limbata essential oil (EO) and extracts from its aerial parts and roots were used to examine the chemical profile and biological activities. The chemical profiles of...

B. H. Akgul, D. Zheleva-Dimitrova, Ł. Świątek et al. · 0 citations
Open access Aug 2026

Phytochemical Characterization of Euphorbia peplis Extracts and Their Antioxidant, Enzyme Inhibitory, and Cytotoxic Activities: An Integrated Experimental and In Silico Study

Findings suggest that E. peplis could be a promising source of antioxidants and compounds with potential anticancer and enzyme‐inhibitory activities relevant to human diseases.

Sakina Yagi, Esraa A. Elhawary, Omayma A. Eldahshna et al. · 0 citations

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