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Ivan A. Sobolevsky

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Open access Sep 2026

Tuning of AMPA receptor activation by inhibitory auxiliary subunits and epilepsy-associated disease mutations

AMPA receptors (AMPARs) facilitate excitatory neurotransmission and are implicated in neurological and neuropsychiatric disorders. Binding of the neurotransmitter glutamate triggers AMPAR activation, which is modulated by potentiating and inhibitory auxiliary subunits. While modulation by potentiating auxiliary subunit...

Thomas P. Newton, M. Yelshanskaya, Muhammed Aktolun et al. · 0 citations

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