This review dissects the hierarchical organization of the synaptome, arguing that synaptic decay is not a generic process of attrition but a specific collapse of subsynaptic domains (SSDs) and trans-synaptic nanocolumns, considered here within the framework of the tetrapartite synapse.
G. Cipriano, Ivan Anchesi, Alessia Floramo et al.· Cells· 0 citations
Neurodegenerative diseases (NDs) are characterized by the progressive deterioration of cognitive and motor functions. In this context, glial cell-mediated neuroinflammation is recognized as a key driver of disease progression. Long non-coding RNAs (lncRNAs) have emerged as key epigenetic regulators that modulate gene e...
Chiara Malatino, Ivana Raffaele, Angelo Quartarone et al.· Frontiers in Aging Neuroscie...· 0 citations
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